DORI researcher, Senta Georgia, PhD has been selected for an oral abstract presentation at the ADA’s 78th Conference

DORI researcher, Senta Georgia, PhD has been selected for an oral abstract presentation at the American Diabetes Association’s 78th Scientific Sessions, June 22-26, 2018 in Orlando, Florida. Her abstract, “CRISPR-Cas9 Gene Editing Restores Beta-Cell Differentiation and Function in Patient-Specific iPSC’s,” will be printed in the Scientific Sessions’ Abstract Book, the July 2018 supplement to the journal Diabetes.

DORI’s 5th Annual Symposium is Feb. 27 & 28, 2018

USC DORI is hosting a no-cost 2-day symposium on February 27 & 28, 2018.
February 27th will begin at 11:00am with 5 speakers and student/postdoc/fellow oral and poster presentations. February 28th will begin at 8:30am with 7 speakers and student/postdoc/fellow oral and poster presentations.

The genetic architecture of type 2 diabetes

The genetic architecture of common traits, including the number, frequency, and effect sizes of inherited variants that contribute to individual risk, has been long debated. Genome-wide association studies have identified scores of common variants associated with type 2 diabetes, but in aggregate, these explain only a fraction of the heritability of this disease.

Gene protects women from heart disease

USC researchers have identified a gene variant that decreases the risk of heart disease — but only among women. Men who carry the variant receive no protective effect.

Hooman Allayee, senior author of the study and associate professor of preventive medicine at the Keck School of Medicine of USC, said scientists have long known that heart disease affects men and women differently, but what causes the difference has not been entirely clear. This new finding may shed light on that mystery.

Hunger Hormone in Infancy May Link to Lifelong Obesity Risk

New study offers hope of future treatments to help prevent weight problems

Researchers at The Saban Research Institute of Children’s Hospital Los Angeles reveal an unexpected role for ghrelin in early brain development and show its long-term impact on appetite regulation. Their study was published online on January 20 by The Journal of Clinical Investigation.

Sugar Linked to Memory Problems in Adolescent Rats

Sugar consumption led to memory problems and brain inflammation.  Studying rats as model subjects, scientists found that adolescents were at an increased risk of suffering negative health effects from sugar-sweetened beverage consumption.