Post: A case for FGF21: The Impact of Dietary Protein Restriction onMetabolic Health and Lifespan by Cristal M. Hill, PhD

Dietary protein restriction (DPR) protects against obesity, improves metabolic health, and extends
lifespan in various organisms. Recent work demonstrated that the beneficial effects of DPR is largely mediated by the liver-derived metabolic hormone FGF21. Other studies report that continuous high levels of FGF21 are associated with extended lifespan, as observed in transgenic mice overexpressing FGF21. Thus, DPR creates a unique approach to define the underlying mechanisms that contribute to these beneficial effects. The central goal of this work is to connect the impact of dietary protein content on metabolism and to identify the potential mechanisms through which reducing protein intake promotes healthy aging.

DATE: Wednesday, March 6, 2024

TIME: 2:00-3:00PM

In-person at:
Torrey Webb Room
Allan Hancock Foundation Building (AHF)
University of Southern California
3616 Trousdale Pkwy
Los Angeles, CA 90089



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